AMPDB_1 | Lipopolysaccharide-binding protein

PEPTIDE SUMMARY

Lipopolysaccharide-binding protein

1 General Description

AMPDB ID: AMPDB_1

Protein Names: Lipopolysaccharide-binding protein (LBP)

Protein Family: BPI LBP Plunc superfamily; BPI LBP family

Gene Name: LBP

Source Organism: Papio anubis (Olive baboon)

Protein Length: 481 AA

Protein Existence: Inferred from homology

2 Protein Sequence & Composition

2.1 Sequence

MGALAGALPSILLALLLTSTPEALGANPGLVARTTDKGLEYAAQEGLLALQSELLRITLPDFTGDVRIPHAGRGSYEFRSLNIHSCELRHSALRPVPSQGLSLSISDSFIRVQGRWKVRKSFLKLQGSFDVSVKGISISVNLLLGSESSGRPTVTASSCSSDIDDVEVDMSGDLGWLLNLFHNQIESKFQKVLKSRICEMIQKSVSSDLQPYLQTLPVTTEIDSFAGVDYSLVEAPRATAQMLEVMFKGEIFHRNHRSPVTLLAPVINLPEEHNKMVYFAVSDYVFNTASLVYHEEGYLNFSITDDMIPPDSNIRLTTKSFRPFVPRLARLYPNMNLELQGSVPSAPLLNFSPGNLSVNPYMEIDAFVLLPSSSKEPVFRLTVATNVSAILTFNTSKITGFLQPGKVKVELKESKVGLFNAELLEALLNYYILNTLYPKFNDKLAEGFPLPLLKRVQLYDLGLQIHKDFLFLGANVQYMRV

FASTA format

2.2 Composition

Counts of Amino Acids

'A': 29, 'R': 22, 'N': 23, 'D': 21, 'C': 3, 'Q': 16, 'E': 26, 'G': 28, 'H': 9, 'I': 23, 'L': 71, 'K': 22, 'M': 10, 'F': 25, 'P': 29, 'S': 48, 'T': 23, 'W': 2, 'Y': 15, 'V': 36

Frequencies of Amino Acids

'A': 6.03%, 'R': 4.57%, 'N': 4.78%, 'D': 4.37%, 'C': 0.62%, 'Q': 3.33%, 'E': 5.41%, 'G': 5.82%, 'H': 1.87%, 'I': 4.78%, 'L': 14.76%, 'K': 4.57%, 'M': 2.08%, 'F': 5.2%, 'P': 6.03%, 'S': 9.98%, 'T': 4.78%, 'W': 0.42%, 'Y': 3.12%, 'V': 7.48%

Missing Amino Acid(s)

No Amino Acid(s) are missing in this protein

Most Occurring Amino Acid(s)

Less Occurring Amino Acid(s)

Hydrophobic Amino Acid(s) Count

253

Hydrophilic Amino Acid(s) Count

228

Basic Amino Acid(s) Count

Acidic Amino Acid(s) Count

Modified Amino Acid(s) Count

Modified Amino Acid(s) Frequencies

Computed by biopython (version 1.79) & proteinAnalysis (version 1)

3 Physicochemical Properties

Sl. No.	Properties	Values	Reference
1.	Molecular Mass	53263.5 Da	Computed by ProtParam module (biopython 1.79)
2.	Aliphatic Index	103.95	Computed by ProtParam module (biopython 1.79)
3.	Instability Index (Half Life)	49.146	Computed by ProtParam module (biopython 1.79)
4.	Hydrophobicity (GRAVY)	0.052	Computed by ProtParam module (biopython 1.79)
5.	Hydrophobic Moment	0.746	Computed by ProtParam module (biopython 1.79)
6.	Isoelectric Point	6.8	Computed by ProtParam module (biopython 1.79)
7.	Charge (at pH 7)	-2.334	Computed by ProtParam module (biopython 1.79)
8.	Secondary Structure Fraction	0.358, 0.266, 0.283 [Helix, Turn, Sheet]	Computed by ProtParam module (biopython 1.79)
9.	Aromaticity	0.087	Computed by ProtParam module (biopython 1.79)
10.	Molar Extinction Coefficient (cysteine\|cystine)	33350, 33475	Computed by ProtParam module (biopython 1.79)

4 Activity Details

4.1 Target Organism(s)

Gram Negative Bacteria

4.2 Antimicrobial Activity

Antibiotic, Antimicrobial, Anti-gram-negative

4.3 Enzymatic Activity

Not found

4.4 Inhibitory Effect

Not found

4.5 Other Biological Activity

Non-hemolytic, Non-ribosomal

Activity data manually curated from Literature and UniProt

5 Database Cross-references

5.1 Literature Database

5.1.1 PubMed

No PMID found

5.2 Protein Sequence Databases

UniProt: A0A096NXF9

5.3 3D Structure Databases

No PDB Ids found

AlphaFoldDB: A0A096NXF9

5.4 Nucleotide Sequence Databases

No entries found in GenBank or EMBL

CCDS: Not found

RefSeq: XP_003904802.1

5.5 Protein-Protein Interaction Databases

STRING: 9555.ENSPANP00000017753

IntAct: Not found

MINT: Not found

DIP: Not found

BioGRID: Not found

5.6 Ligand Databases

BindingDB: Not found

DrugBank: Not found

ChEMBL: Not found

5.7 Family & Domain Databases

InterPro: IPR017943, IPR030675, IPR032942, IPR030180, IPR001124, IPR017942

PANTHER: PTHR10504, PTHR10504:SF66

PROSITE: Not found

5.8 Genome Annotation Databases

Ensembl: ENSGT01070000253841

KEGG: panu:101017759

5.9 Phylogenomic Databases

GeneTree: ENSGT01070000253841

5.10 Enzyme & Pathway Databases

BRENDA: Not found

BioCyc: Not found

5.11 Protein-RNA Interaction Databases

RNAct: Not found

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